• At Tromborg, our in-house science team develops innovative skincare products that expand the age of your skin on a molecular level by means of bioactive ingredients.

Anti-aging on a molecular level

Aging of the skin is caused by a cycle of biochemical processes that degenerate your body’s largest organ, the skin, over time and, as a result, affect its appearance. Aging of the skin is charaterised by outer traits such as wrinkles, loss of elasticity and plumpness. When we work with Anti-Aging in Tromborg, we refer to the process of limiting or delaying these changes through the help of a series of skincare products on a molecular level.

Anti-Aging product formulations are the result of developing front-line technologies and using powerful ingredients such as sophisticated, biotechnological peptides.

Based on our own in-house research, Tromborg works on reprogramming the skin cells in order to minimise skin aging through Tromborg’s favourite ingredients: plant extracts and peptides.

We always work with the newest research within biotechnology and use bioactive ingredients, such as peptides, in combination with organic plant extracts (Biointelligence®). Anti-aging is an attempt to take good care of the skin cells throughout your entire life to achieve beautiful, glowing and vital skin. After all, the skin is the largest organ of your body. For that exact purpose, Tromborg has developed Treatment and Beaty of North©. Two series of anti-aging products that expand and extend the age of the skin by working with anti-aging on a molecular level.

  • We call it Science Behind Beauty©, which together with organic active ingredients act as the foundation of our skincare products.

Epidermis & Dermis

Anti-aging concerns itself with the upper two layers of the skin: the epidermis (outermost layer) and the dermis (middle layer).

Read more about epidermis and dermis

The epidermis is the outermost layer of the skin, where the primary cellular type is keratinocytes. The epidermis makes up the barrier to your surroundings, wherein the keratinocytes prevent external substances (heat, UV radiation, bacteria, etc.) from penetrating the skin. The epidermis is constantly being bombarded with particulate matter and free radicals. Both can attack skin cells and damage the skin barrier.

The border between the epidermis and dermis, the dermal-epidermal junction (DEJ), is a collection of proteins and structures known as the basal membrane. Beneath the basal membrane, you find the subjacent dermis, which provides structural support together with nourishment and circulation within in skin. Here, we find macromolecules and it’s also here that permanent or damaging changes in the skin occur. Tromborg’s biochemist, Tim Schyberg, mainly works with the dermis when developing new, ground-breaking skincare products to counteract the aging of the skin.


Aging-related changes in skin layers have a substantial impact on the aesthetic view of the skin, appearance and feeling, such as wrinkles and loss of elasticity. The aging of the skin is further accelerated by external factors such as air pollution, smoking and sun exposure (UV radiation). In our day-to-day life, we are not able to constantly avoid all these factors that age our skin.  This is why Tromborg develops products that protect against external aging of your skin, so we can give the skin the right help to counteract signs of aging on a molecular level.

One example of such help is Tromborg’s bio-magical Biomolecular Destress Peptide Mist which protects the skin by stimulating the production of so-called heat shock proteins, which help to protect the cells against stress caused by various external phenomena, including chemical stressors and constant temperature changes. Further, the mist also boosts the biomolecular effect of bioactive ingredients in other Tromborg products.

The by far worst damage the skin is subjected to is UV radiation from the sun, also known as photoaging. The radiation damages the DNA of the skin cells because the sun generates reactive oxygen species (ROS) that severely damage the changes in your skin cells. To avoid ROS damage, it is crucial that you always wear sun protection before venturing out into the sun.

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ROS is the primary factor behind aging and fatigue of the skin cells, as it destroys the skin barrier and damages mitochondrial DNA that acts as the cell’s energy centres and produces ATP. ATP are energy-carrying molecules that are the most crucial source of energy in our cells. Tromborg’s Sun Primer DNA Protection Cream is enriched with 20 natural active ingredients, including antioxidants that work together to neutralise the negative effect of free radicals caused by free radicals from UV radiation and environmental factors. In addition, you should always use sun protection for protecting your skin when exposed to the sun.


Not only does the sun leads to increased ROS in the dermis. From the age of 30, the skin starts to produce ROS. The fact that your skin starts to noticeably age from the age of 30 is due to a mutation in the human genes – a so-called genetic defect. For instance, a specific species of clams does not have this age-advancing genetic defect, meaning that they can become over 500 years old.

To understand how the skin ages due to age and external radiation, we must take a closer look at the middle layer of the skin, dermis. Dermis primarily consists of an extracellular matrix (ECM) and fibroblasts which are cells in the connective tissue. When the ECM is balanced, the skin remains healthy and vital. Fibroblasts enable synthesis and degradation in ECM. In young skin, these fibroblasts function as a factory for producing collagen, elasticity and similar components that make the skin appear smooth and young. The balance between synthesis and degradation of the ECM creates a state of homeostasis. When the balance in the ECM is disturbed, it results in wrinkles and less elastic skin.

Read more

In young skin, large amounts of fibroblasts produce collagen. However, as the skin begins to age, the fibroblasts decay and start to produce a larger amount of ROS that increases the MMP concentration. MMP (matrix metalloproteinases) are aggressive enzymes that degrade collagen and other ECM proteins. It’s necessary to reduce the MMP in order to maintain skin elasticity and expand the skin’s age on a molecular level. The increased MMP activity is induced by free radicals that break down ECM molecules, leading to collagen fragmentation and thus, accelerated dermal aging. This degradation of the skin balance and collagen level appears as wrinkles and dry patches on the surface of the skin.

Older ECMs are characterised by a loss of collagen mass and accumulation of protein aggregates, that they become fragmented and that they lose their protective and mechanical functions, which are essential for cellular integrity. When restoring the ECM homeostasis through anti-aging, you can reduce wrinkles and recreate the skin’s cosmetic look. The peptides in Tromborg’s products, such as our Peptide Anti-Aging Wrinkle Serum, slow down the skin’s aging by activating the construction of collagen and ECM.

In human skin, the amount of collagen is subjected to a continuous fall of 1% yearly, which results in wrinkles and loose and tired-looking skin. Generally speaking, during aging, there is a decrease in ECM-biosynthesis followed by an increase in ECM degradation. This loss of ECM biosynthesis and the increase of ECM degradation might drive or expedite the aging of the skin, which we attempt to slow down with products containing peptide complexes that work as signal molecules (‘messengers’) and have a documented anti-aging effect.


When your skin ages, the basal lamina is the first to get attacked and affected. The basal membrane lamina separates the two upper layers of the skin, epidermis and dermis. In young skin, the basal lamina membrane is contracted and wrinkly-looking which means that your skin appears smooth on the surface. As the skin starts getting older and less elastic, the basal membrane is stretched out - and that’s when the wrinkles start appearing on the surface of the skin.

How does anti-aging work?

With anti-aging on a molecular level, innovative and bio-active ingredients (messengers) in a particular skincare product will provide a series of cosmetic benefits for the skin: reduced wrinkles on the skin’s surface, firmed skin, moisturized skin and increased elasticity. This is done by recreating balance to achieve homeostasis between the ECM degradation and ECM synthesis. In particular, we attempt to boost the synthesis by teaching the skin cells how to behave as younger skin for a longer period of time. This is done by expanding the skin’s age on a molecular level, while you simultaneously counteract the negative degradation processes in order to avoid the breakdown of existing collagen in your body.

Tromborg’s Treatment line utilises the newest anti-aging research and puts it in a molecular context in order to expand the skin’s age. We unite nature and science with products containing plant extracts and the newest peptide technology such as 4-generation peptides. To counteract the skin’s aging process on a molecular level, you must use a large quantity of bio-active ingredients. The more bio-active ingredients, the bigger chance of a cosmetic effect.

  • Because of the effect of bio-active ingredients, our Anti-Aging Wrinkle Cream contains no less than 35 active ingredients and 6 peptides – with an ingredient list like that, you get a visible result where fine lines and wrinkles are reduced. 

The many bio-active ingredients affect the aging-related molecular processes in the skin in order to reduce visible signs of aging.

State-of-the-art knowledge together with our continuous research within anti-aging on a molecular level has led us to develop a breakthrough within skincare: The Beauty of North line combines an unprecedented number of 11 different peptides with Wild Type® Plants (plants growing wild in their natural habitats, what we have called ‘Above Organic’). In Anti-Aging Molecular Messenger Cream, a cyclopeptide reduces visible signs of wrinkles and provides plump and elastic skin, while a mixture of tri and tetra peptides enrich the cream with a new dimension of smoothness. Anti-Aging at the highest possible level.

With an effective anti-aging skincare routine from Tromborg, you will achieve visible results with smoother skin where fine lines and wrinkles are visibly reduced. The active moisturizers can also be applied already from your 20s to prevent the appearance of wrinkles and strengthen collagen. Further, anti-aging products are the ultimate moisture boosters no matter your skin type. It is bio-intelligence at the highest possible level that is efficient for your skin. No matter your age.



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